Melasma: Treatment Modalities and New Therapeutic Strategies

Abstract

      Melasma is a common distressing skin condition with symmetrical brown or gray-brown patches on the face. It affects women, especially during their reproductive years, posing not only aesthetic challenges but also psychological impacts, as it can decrease quality of life and self-esteem. Various factors contribute to this condition, including family history, exposure to ultraviolet radiation (UV) and hormonal imbalances. Management of melasma is challenging and vary based on the depth and extent of pigmentation, as well as individual patient factors. Our review summarizes the various current therapeutic modalities used in the treatment of melasma and their side effect profile in addition to the new therapeutic strategies that may benefit melasma patients.