Fibrinogen to Albumin Ratio in Acute Kidney Injury: A Readily Available Biomarker for Critical Illness Outcomes

Abstract

Background: Acute kidney injury (AKI) is a frequent and serious complication in critically ill patients, associated with high morbidity, mortality, and healthcare burden. Despite advances in critical care, early recognition and precise risk stratification of AKI remain challenging, contributing to delays in intervention and poor outcomes. In recent years, a growing focus has emerged on the role of biomarkers in enhancing the timely diagnosis and prognosis of AKI. Among these, the fibrinogen to albumin ratio (FAR) has gained attention as a potential prognostic marker due to its reflection of systemic inflammation and nutritional status—both of which are crucial determinants of outcomes in critically ill populations