Efficiently Deliver Gemcitabine to the Tumor Leading to Higher Therapeutic Benefit as Compared to the Drug in Solution

Authors

  • Dr. Huda Begam

Keywords:

Gemcitabine, drug delivery systems, nanoparticles, tumor targeting, enhanced permeability and retention effect, cancer therapy, nanotechnology

Abstract

Gemcitabine (2′,2′-difluoro-2′-deoxycytidine) is a nucleoside analog chemotherapeutic agentwidely used as first-line therapy for pancreatic cancer and other solid tumors. However, itsclinical efficacy is severely limited by rapid enzymatic degradation

References

Shi, M., Zhao, Y., Zhang, H., et al. (2024). Antibody-DNA nanostructure conjugate enables targeted delivery of gemcitabine to tumor and improves the anti-tumor efficacy. Science Direct, Available at: https://www.sciencedirect.com/science/article/abs/pii/S0168365925002305

Downloads

Published

2024-05-15

How to Cite

Dr. Huda Begam. (2024). Efficiently Deliver Gemcitabine to the Tumor Leading to Higher Therapeutic Benefit as Compared to the Drug in Solution . Journal of Computational Analysis and Applications (JoCAAA), 33(05), 2171–2184. Retrieved from https://www.eudoxuspress.com/index.php/pub/article/view/3254

Issue

Vol. 33 No. 05 (2024): JOCAAA

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.